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Belinostat

CAS No. 414864-00-9

Belinostat ( PXD101 )

Catalog No. M14420 CAS No. 414864-00-9

Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 35 In Stock
10MG 56 In Stock
25MG 88 In Stock
50MG 132 In Stock
100MG 195 In Stock
200MG 312 In Stock
500MG 520 In Stock
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Biological Information

  • Product Name
    Belinostat
  • Note
    Research use only, not for human use.
  • Brief Description
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
  • Description
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
  • Synonyms
    PXD101
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    414864-00-9
  • Formula Weight
    318.35
  • Molecular Formula
    C15H14N2O4S
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 64 mg/mL (201.03 mM)
  • SMILES
    C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
  • Chemical Name
    2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Savickiene J, et al. anticancer Drugs. 2014 Sep;25(8):938-49.
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